Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes

GBPs are essential for immunity against intracellular pathogens, especially for Toxoplasma gondii control. Here, the molecular interactions of murine GBPs (mGBP1/2/3/5/6), homo- and hetero-multimerization properties of mGBP2 and its function in parasite killing were investigated by mutational, Multi...

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Detalhes bibliográficos
Publicado no:eLife
Principais autores: Kravets, Elisabeth, Degrandi, Daniel, Ma, Qijun, Peulen, Thomas-Otavio, Klümpers, Verena, Felekyan, Suren, Kühnemuth, Ralf, Weidtkamp-Peters, Stefanie, Seidel, Claus AM, Pfeffer, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786432/
https://ncbi.nlm.nih.gov/pubmed/26814575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11479
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