Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α

Adolescents are particularly vulnerable to nicotine, the principal addictive component driving tobacco smoking. In a companion study, we found that reduced activity of the translation initiation factor eIF2α underlies the hypersensitivity of adolescent mice to the effects of cocaine. Here we report...

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Vydáno v:eLife
Hlavní autoři: Placzek, Andon N, Molfese, David L, Khatiwada, Sanjeev, Viana Di Prisco, Gonzalo, Huang, Wei, Sidrauski, Carmela, Krnjević, Krešimir, Amos, Christopher L, Ray, Russell, Dani, John A, Walter, Peter, Salas, Ramiro, Costa-Mattioli, Mauro
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786418/
https://ncbi.nlm.nih.gov/pubmed/26928076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12056
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