Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

The nucleolus is a membrane-less organelle formed through liquid-liquid phase separation of its components from the surrounding nucleoplasm. Here, we show that nucleophosmin (NPM1) integrates within the nucleolus via a multi-modal mechanism involving multivalent interactions with proteins containing...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mitrea, Diana M, Cika, Jaclyn A, Guy, Clifford S, Ban, David, Banerjee, Priya R, Stanley, Christopher B, Nourse, Amanda, Deniz, Ashok A, Kriwacki, Richard W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Structural Biology and Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786410/
https://ncbi.nlm.nih.gov/pubmed/26836305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13571
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados