Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice

Kainic acid (KA) is routinely used to elicit status epilepticus (SE) and epileptogenesis. Among the available KA administration protocols, intranasal instillation (IN) remains understudied. Dosages of KA were instilled IN in mice. Racine Scale and Video-EEG were used to assess and quantify SE onset....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sabilallah, Mounira, Fontanaud, Pierre, Linck, Nathalie, Boussadia, Badreddine, Peyroutou, Ronan, Lasgouzes, Thibault, Rassendren, François A., Marchi, Nicola, Hirbec, Helene E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786335/
https://ncbi.nlm.nih.gov/pubmed/26963100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150793
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