Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice

Kainic acid (KA) is routinely used to elicit status epilepticus (SE) and epileptogenesis. Among the available KA administration protocols, intranasal instillation (IN) remains understudied. Dosages of KA were instilled IN in mice. Racine Scale and Video-EEG were used to assess and quantify SE onset....

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Sabilallah, Mounira, Fontanaud, Pierre, Linck, Nathalie, Boussadia, Badreddine, Peyroutou, Ronan, Lasgouzes, Thibault, Rassendren, François A., Marchi, Nicola, Hirbec, Helene E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786335/
https://ncbi.nlm.nih.gov/pubmed/26963100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150793
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