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Loss of ATP-Sensitive Potassium Channel Surface Expression in Heart Failure Underlies Dysregulation of Action Potential Duration and Myocardial Vulnerability to Injury

The search for new approaches to treatment and prevention of heart failure is a major challenge in medicine. The adenosine triphosphate-sensitive potassium (K(ATP)) channel has been long associated with the ability to preserve myocardial function and viability under stress. High surface expression o...

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Pubblicato in:PLoS One
Autori principali: Gao, Zhan, Sierra, Ana, Zhu, Zhiyong, Koganti, Siva Rama Krishna, Subbotina, Ekaterina, Maheshwari, Ankit, Anderson, Mark E., Zingman, Leonid V., Hodgson-Zingman, Denice M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786327/
https://ncbi.nlm.nih.gov/pubmed/26964104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151337
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