Loss of ATP-Sensitive Potassium Channel Surface Expression in Heart Failure Underlies Dysregulation of Action Potential Duration and Myocardial Vulnerability to Injury

The search for new approaches to treatment and prevention of heart failure is a major challenge in medicine. The adenosine triphosphate-sensitive potassium (K(ATP)) channel has been long associated with the ability to preserve myocardial function and viability under stress. High surface expression o...

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Udgivet i:PLoS One
Main Authors: Gao, Zhan, Sierra, Ana, Zhu, Zhiyong, Koganti, Siva Rama Krishna, Subbotina, Ekaterina, Maheshwari, Ankit, Anderson, Mark E., Zingman, Leonid V., Hodgson-Zingman, Denice M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786327/
https://ncbi.nlm.nih.gov/pubmed/26964104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151337
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