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Characterization of broken DNA molecules associated with V(D)J recombination.

We previously demonstrated that DNA molecules with double-strand breaks at variable-(diversity)-joining [V(D)J] recombination signal sequences are relatively abundant in mouse thymocytes. This abundance strongly suggests that the mechanism of V(D)J recombination involves double-strand cleavage at re...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Roth, D B, Zhu, C, Gellert, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10788
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