Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer

Blockade of epidermal growth factor receptor (EGFR) activity has been a primary therapeutic target for non-small cell lung cancers (NSCLC). As patients with wild-type EGFR have demonstrated only modest benefit from EGFR tyrosine kinase inhibitors (TKIs), there is a need for additional therapeutic ap...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Howe, Grant A., Xiao, Bin, Zhao, Huijun, Al-Zahrani, Khalid N., Hasim, Mohamed S., Villeneuve, James, Sekhon, Harmanjatinder S., Goss, Glenwood D., Sabourin, Luc A., Dimitroulakos, Jim, Addison, Christina L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786279/
https://ncbi.nlm.nih.gov/pubmed/26962872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150567
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