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IL-10 Production Is Critical for Sustaining the Expansion of CD5(+) B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice

The development and progression of systemic lupus erythematosus is mediated by the complex interaction of genetic and environmental factors. To decipher the genetics that contribute to pathogenesis and the production of pathogenic autoantibodies, our lab has focused on the generation of congenic lup...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Baglaenko, Yuriy, Manion, Kieran P., Chang, Nan-Hua, Gracey, Eric, Loh, Christina, Wither, Joan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786215/
https://ncbi.nlm.nih.gov/pubmed/26964093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150515
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