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Role of Biomarkers in the Development of PARP Inhibitors

Defects in DNA repair lead to genomic instability and play a critical role in cancer development. Understanding the process by which DNA damage repair is altered or bypassed in cancer may identify novel therapeutic targets and lead to improved patient outcomes. Poly(adenosine diphosphate-ribose) pol...

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Vydáno v:Biomark Cancer
Hlavní autoři: Ganguly, Bratati, Dolfi, Sonia C., Rodriguez-Rodriguez, Lorna, Ganesan, Shridar, Hirshfield, Kim M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Libertas Academica 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786099/
https://ncbi.nlm.nih.gov/pubmed/26997874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BIC.S36679
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