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Evolution of E. coli on [U-(13)C]Glucose Reveals a Negligible Isotopic Influence on Metabolism and Physiology

(13)C-Metabolic flux analysis ((13)C-MFA) traditionally assumes that kinetic isotope effects from isotopically labeled compounds do not appreciably alter cellular growth or metabolism, despite indications that some biochemical reactions can be non-negligibly impacted. Here, populations of Escherichi...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Sandberg, Troy E., Long, Christopher P., Gonzalez, Jacqueline E., Feist, Adam M., Antoniewicz, Maciek R., Palsson, Bernhard O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786092/
https://ncbi.nlm.nih.gov/pubmed/26964043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151130
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