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Characterization of physiological responses to 22 gene knockouts in Escherichia coli central carbon metabolism

Understanding the impact of gene knockouts on cellular physiology, and metabolism in particular, is centrally important to quantitative systems biology and metabolic engineering. Here, we present a comprehensive physiological characterization of wild-type Escherichia coli and 22 knockouts of enzymes...

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發表在:Metab Eng
Main Authors: Long, Christopher P., Gonzalez, Jacqueline E., Sandoval, Nicholas R., Antoniewicz, Maciek R.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845446/
https://ncbi.nlm.nih.gov/pubmed/27212692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2016.05.006
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