Hematopoietic Reprogramming in vitro Informs in vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells

Definitive hematopoiesis emerges via an endothelial-to-hematopoietic transition in the embryo and placenta; however, the precursor cells to hemogenic endothelium are not defined phenotypically. We previously demonstrated that the induction of hematopoietic progenitors from fibroblasts progresses thr...

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Publicado en:Dev Cell
Main Authors: Pereira, Carlos-Filipe, Chang, Betty, Gomes, Andreia, Bernitz, Jeffrey, Papatsenko, Dmitri, Niu, Xiaohong, Swiers, Gemma, Azzoni, Emanuele, de Bruijn, Marella F. T. R., Schaniel, Christoph, Lemischka, Ihor R., Moore, Kateri A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785845/
https://ncbi.nlm.nih.gov/pubmed/26954547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.02.011
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