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Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

Although there is considerable evidence that a subpopulation of regulatory CD4(+)CD25(+) T cells can suppress the response of autoreactive T cells, the underlying molecular mechanism is not understood. We find that transmission of a suppressive signal by CD4CD25(+) regulatory cells requires engageme...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Paust, Silke, Lu, Linrong, McCarty, Nami, Cantor, Harvey
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15235129/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403342101
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