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Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

Although there is considerable evidence that a subpopulation of regulatory CD4(+)CD25(+) T cells can suppress the response of autoreactive T cells, the underlying molecular mechanism is not understood. We find that transmission of a suppressive signal by CD4CD25(+) regulatory cells requires engageme...

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Detalhes bibliográficos
Main Authors: Paust, Silke, Lu, Linrong, McCarty, Nami, Cantor, Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC478583/
https://ncbi.nlm.nih.gov/pubmed/15235129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403342101
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