Overexpression of human loricrin in transgenic mice produces a normal phenotype.
The cornified cell envelope (CE) of terminally differentiating stratified squamous epithelial cells is a complex multiprotein assembly about 15 nm thick of which loricrin is a major component. We have produced transgenic mice bearing the human loricrin transgene in order to study the role of loricri...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10754 |
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