Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus – Insights into a novel pro-drug approach addressing MRSA infections

Infections caused by the methicillin-resistant Staphylococcus aureus (MRSA) are today known to be a substantial threat for global health. Emerging multi-drug resistant bacteria have created a substantial need to identify and discover new drug targets and to develop novel strategies to treat bacteria...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Drebes, Julia, Künz, Madeleine, Windshügel, Björn, Kikhney, Alexey G., Müller, Ingrid B., Eberle, Raphael J., Oberthür, Dominik, Cang, Huaixing, Svergun, Dmitri I., Perbandt, Markus, Betzel, Christian, Wrenger, Carsten
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785402/
https://ncbi.nlm.nih.gov/pubmed/26960569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22871
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