Prediction of Mechanisms of Action of Antibacterial Compounds by Gene Expression Profiling

We have generated a database of expression profiles carrying the transcriptional responses of the model organism Bacillus subtilis following treatment with 37 well-characterized antibacterial compounds of different classes. The database was used to build a predictor for the assignment of the mechani...

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Main Authors: Hutter, Bernd, Schaab, Christoph, Albrecht, Sebastian, Borgmann, Matthias, Brunner, Nina A., Freiberg, Christoph, Ziegelbauer, Karl, Rock, Charles O., Ivanov, Igor, Loferer, Hannes
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC478524/
https://ncbi.nlm.nih.gov/pubmed/15273089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2838-2844.2004
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