Molecular Characterization of a Cephamycin-Hydrolyzing and Inhibitor-Resistant Class A β-Lactamase, GES-4, Possessing a Single G170S Substitution in the Ω-Loop

The nosocomial spread of six genetically related Klebsiella pneumoniae strains producing GES-type β-lactamases was found in a neonatal intensive care unit, and we previously reported that one of the six strains, strain KG525, produced a new β-lactamase, GES-3. In the present study, the molecular mec...

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Main Authors: Wachino, Jun-ichi, Doi, Yohei, Yamane, Kunikazu, Shibata, Naohiro, Yagi, Tetsuya, Kubota, Takako, Arakawa, Yoshichika
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
Mechanisms of Resistance
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC478515/
https://ncbi.nlm.nih.gov/pubmed/15273099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2905-2910.2004
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