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Activities of Different Fluoroquinolones against Bacillus anthracis Mutants Selected In Vitro and Harboring Topoisomerase Mutations

Three sets of mutants of Bacillus anthracis resistant to fluoroquinolones were selected on ciprofloxacin and moxifloxacin in a stepwise manner from a nalidixic acid-resistant but fluoroquinolone-susceptible plasmidless strain harboring a Ser85Leu GyrA mutation. A high level of resistance to fluoroqu...

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Autors principals: Grohs, Patrick, Podglajen, Isabelle, Gutmann, Laurent
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC478509/
https://ncbi.nlm.nih.gov/pubmed/15273116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3024-3027.2004
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