A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function

Activation of brown and beige fat can reduce obesity and improve glucose homeostasis through non-shivering thermogenesis. Whether brown or beige fat also secrete paracrine or endocrine factors to promote and amplify adaptive thermogenesis is not fully explored. Here we identify Slit2, a 180 kDa memb...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Svensson, Katrin J., Long, Jonathan Z., Jedrychowski, Mark P., Cohen, Paul, Lo, James C., Serag, Sara, Kir, Serkan, Shinoda, Kosaku, Tartaglia, Julia A., Rao, Rajesh R., Chédotal, Alain, Kajimura, Shingo, Gygi, Steven P., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785066/
https://ncbi.nlm.nih.gov/pubmed/26876562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.01.008
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