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Unraveling the Mode of Action of the Antimalarial Choline Analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae

Pharmacological studies have indicated that the choline analog G25 is a potent inhibitor of Plasmodium falciparum growth in vitro and in vivo. Although choline transport has been suggested to be the target of G25, the exact mode of action of this compound is not known. Here we show that, similar to...

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Bibliografische gegevens
Hoofdauteurs: Roggero, Rodolphe, Zufferey, Rachel, Minca, Mihaela, Richier, Eric, Calas, Michele, Vial, Henri, Mamoun, Choukri Ben
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC478495/
https://ncbi.nlm.nih.gov/pubmed/15273086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2816-2824.2004
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