Disposition of Artesunate and Dihydroartemisinin after Administration of Artesunate Suppositories in Children from Papua New Guinea with Uncomplicated Malaria

A detailed pharmacokinetic analysis was performed with 47 children from Papua New Guinea with uncomplicated falciparum or vivax malaria treated with artesunate (ARTS) suppositories (Rectocaps) given in two doses of approximately 13 mg/kg of body weight 12 h apart. Following an intensive sampling pro...

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Autors principals: Karunajeewa, Harin A., Ilett, Kenneth F., Dufall, Kitiya, Kemiki, Adedayo, Bockarie, Moses, Alpers, Michael P., Barrett, P. Hugh, Vicini, Paolo, Davis, Timothy M. E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC478493/
https://ncbi.nlm.nih.gov/pubmed/15273107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2966-2972.2004
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