Disposition of Artesunate and Dihydroartemisinin after Administration of Artesunate Suppositories in Children from Papua New Guinea with Uncomplicated Malaria

A detailed pharmacokinetic analysis was performed with 47 children from Papua New Guinea with uncomplicated falciparum or vivax malaria treated with artesunate (ARTS) suppositories (Rectocaps) given in two doses of approximately 13 mg/kg of body weight 12 h apart. Following an intensive sampling pro...

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Detalhes bibliográficos
Main Authors: Karunajeewa, Harin A., Ilett, Kenneth F., Dufall, Kitiya, Kemiki, Adedayo, Bockarie, Moses, Alpers, Michael P., Barrett, P. Hugh, Vicini, Paolo, Davis, Timothy M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC478493/
https://ncbi.nlm.nih.gov/pubmed/15273107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.2966-2972.2004
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