Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes

The aim of this study was to evaluate the impact of different inactivation and splitting procedures on influenza vaccine product composition, stability and recovery to support transfer of process technology. Four split and two whole inactivated virus (WIV) influenza vaccine bulks were produced and c...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kon, Theone C., Onu, Adrian, Berbecila, Laurentiu, Lupulescu, Emilia, Ghiorgisor, Alina, Kersten, Gideon F., Cui, Yi-Qing, Amorij, Jean-Pierre, Van der Pol, Leo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784929/
https://ncbi.nlm.nih.gov/pubmed/26959983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150700
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