Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes

The aim of this study was to evaluate the impact of different inactivation and splitting procedures on influenza vaccine product composition, stability and recovery to support transfer of process technology. Four split and two whole inactivated virus (WIV) influenza vaccine bulks were produced and c...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kon, Theone C., Onu, Adrian, Berbecila, Laurentiu, Lupulescu, Emilia, Ghiorgisor, Alina, Kersten, Gideon F., Cui, Yi-Qing, Amorij, Jean-Pierre, Van der Pol, Leo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784929/
https://ncbi.nlm.nih.gov/pubmed/26959983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150700
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