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Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing

A key challenge in the SAD phasing method is solving a structure when the anomalous signal-to-noise ratio is low. A simple theoretical framework for describing measurements of anomalous differences and the resulting useful anomalous correlation and anomalous signal in a SAD experiment is presented....

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Publicat a:Acta Crystallogr D Struct Biol
Autors principals: Terwilliger, Thomas C., Bunkóczi, Gábor, Hung, Li-Wei, Zwart, Peter H., Smith, Janet L., Akey, David L., Adams, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784666/
https://ncbi.nlm.nih.gov/pubmed/26960122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798315019269
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