The activation of M3 mAChR in airway epithelial cells promotes IL-8 and TGF-β1 secretion and airway smooth muscle cell migration

BACKGROUND: Muscarinic acetylcholine receptors (mAChRs) have been identified in airway epithelium, and epithelium-derived chemokines can initiate the migration of airway smooth muscle (ASM) cells. However, the mAChRs that are expressed in airway epithelium and the mechanism underlying the regulation...

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發表在:Respir Res
Main Authors: Lu, Juan-Juan, Xu, Guang-Ni, Yu, Ping, Song, Yun, Wang, Xiao-Lin, Zhu, Liang, Chen, Hong-Zhuan, Cui, Yong-Yao
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784334/
https://ncbi.nlm.nih.gov/pubmed/26956674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0344-5
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