The activation of M3 mAChR in airway epithelial cells promotes IL-8 and TGF-β1 secretion and airway smooth muscle cell migration

BACKGROUND: Muscarinic acetylcholine receptors (mAChRs) have been identified in airway epithelium, and epithelium-derived chemokines can initiate the migration of airway smooth muscle (ASM) cells. However, the mAChRs that are expressed in airway epithelium and the mechanism underlying the regulation...

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Enregistré dans:
Détails bibliographiques
Publié dans:Respir Res
Auteurs principaux: Lu, Juan-Juan, Xu, Guang-Ni, Yu, Ping, Song, Yun, Wang, Xiao-Lin, Zhu, Liang, Chen, Hong-Zhuan, Cui, Yong-Yao
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784334/
https://ncbi.nlm.nih.gov/pubmed/26956674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0344-5
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