The activation of M3 mAChR in airway epithelial cells promotes IL-8 and TGF-β1 secretion and airway smooth muscle cell migration

BACKGROUND: Muscarinic acetylcholine receptors (mAChRs) have been identified in airway epithelium, and epithelium-derived chemokines can initiate the migration of airway smooth muscle (ASM) cells. However, the mAChRs that are expressed in airway epithelium and the mechanism underlying the regulation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Respir Res
Prif Awduron: Lu, Juan-Juan, Xu, Guang-Ni, Yu, Ping, Song, Yun, Wang, Xiao-Lin, Zhu, Liang, Chen, Hong-Zhuan, Cui, Yong-Yao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784334/
https://ncbi.nlm.nih.gov/pubmed/26956674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0344-5
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