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Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications

Low maternal circulating concentrations of placental growth factor (PlGF) are one of the hallmarks of human pregnancy complications, including fetal growth restriction (FGR) and early‐onset pre‐eclampsia (PE). Currently, PlGF is used clinically with other biomarkers to screen for high‐risk cases, al...

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Bibliografski detalji
Izdano u:J Pathol
Glavni autori: Mizuuchi, Masahito, Cindrova‐Davies, Tereza, Olovsson, Matts, Charnock‐Jones, D Stephen, Burton, Graham J, Yung, Hong Wa
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784173/
https://ncbi.nlm.nih.gov/pubmed/26648175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4678
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