Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy complications

Low maternal circulating concentrations of placental growth factor (PlGF) are one of the hallmarks of human pregnancy complications, including fetal growth restriction (FGR) and early‐onset pre‐eclampsia (PE). Currently, PlGF is used clinically with other biomarkers to screen for high‐risk cases, al...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: Mizuuchi, Masahito, Cindrova‐Davies, Tereza, Olovsson, Matts, Charnock‐Jones, D Stephen, Burton, Graham J, Yung, Hong Wa
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2016
Sujets:
Original Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784173/
https://ncbi.nlm.nih.gov/pubmed/26648175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4678
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