Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction

We recently reported the first evidence of placental endoplasmic reticulum (ER) stress in the pathophysiology of human intrauterine growth restriction. Here, we used a mouse model to investigate potential underlying mechanisms. Eif2s1(tm1RjK) mice, in which Ser51 of eukaryotic initiation factor 2 su...

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Bibliografiska uppgifter
Huvudupphovsmän: Yung, Hong wa, Hemberger, Myriam, Watson, Erica D, Senner, Claire E, Jones, Carolyn P, Kaufman, Randal J, Charnock-Jones, D Stephen, Burton, Graham J
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Ltd 2012
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532660/
https://ncbi.nlm.nih.gov/pubmed/22733590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4068
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