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Vitamins A and D have antagonistic effects on expression of effector cytokines and gut-homing integrin in human innate lymphoid cells

BACKGROUND: Retinoic acid (RA), the main biologically active metabolite of vitamin A, is known to promote gut homing of lymphocytes, as well as various regulatory and effector immune responses. In contrast, the active form of vitamin D, 1,25-dihydroxyvitamin D(3 ()1,25D3), is predominantly immunosup...

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Veröffentlicht in:Clin Exp Allergy
Hauptverfasser: Ruiter, Bert, Patil, Sarita U., Shreffler, Wayne G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784097/
https://ncbi.nlm.nih.gov/pubmed/25959810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12568
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