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Crystal structure of the RNA-dependent RNA polymerase from influenza C virus

Negative-sense RNA viruses, such as influenza, encode large, multidomain RNA-dependent RNA polymerases that can both transcribe and replicate the viral RNA genome(1). In influenza virus, the polymerase (FluPol) is composed of three polypeptides: PB1, PB2 and PA/P3. PB1 houses the polymerase active s...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Hengrung, Narin, El Omari, Kamel, Martin, Itziar Serna, Vreede, Frank T., Cusack, Stephen, Rambo, Robert P., Vonrhein, Clemens, Bricogne, Gérard, Stuart, David I., Grimes, Jonathan M., Fodor, Ervin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783868/
https://ncbi.nlm.nih.gov/pubmed/26503046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15525
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