C-reactive protein levels and body mass index: Elucidating direction of causation through reciprocal Mendelian randomization

CONTEXT: The assignment of direction and causality within networks of observational associations is problematic outside randomized control trials and the presence of causal a relationship between body mass index (BMI) and C-reactive protein (CRP) is disputed. OBJECTIVE: Using reciprocal Mendelian ra...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Timpson, Nicholas J., Nordestgaard, Børge G., Harbord, Roger M., Zacho, Jeppe, Frayling, Tim M., Tybjærg-Hansen, Anne, Smith, George Davey
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783860/
https://ncbi.nlm.nih.gov/pubmed/20714329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2010.137
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