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In vivo reprogramming reactive glia into iPSCs to produce new neurons in the cortex following traumatic brain injury

Traumatic brain injury (TBI) results in a significant amount of cell death in the brain. Unfortunately, the adult mammalian brain possesses little regenerative potential following injury and little can be done to reverse the initial brain damage caused by trauma. Reprogramming adult cells to generat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gao, Xiang, Wang, Xiaoting, Xiong, Wenhui, Chen, Jinhui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783661/
https://ncbi.nlm.nih.gov/pubmed/26957147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22490
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