TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages

Pathogenic bacteria have evolved multiple mechanisms to capture iron or iron-containing heme from host tissues or blood. In response, organisms have developed defense mechanisms to keep iron from pathogens. Very little of the body's iron store is available as free heme; rather nearly all body i...

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Bibliografiske detaljer
Udgivet i:J Immunol Res
Main Authors: Philip, Mary, Chiu, Edison Y., Hajjar, Adeline M., Abkowitz, Janis L.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783552/
https://ncbi.nlm.nih.gov/pubmed/27006955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4039038
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