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Heme exporter FLVCR is required for T cell development and peripheral survival

All aerobic cells and organisms must synthesize heme from the amino acid glycine and the tricarboxylic acid (TCA) cycle intermediate succinyl Coenzyme A for incorporation into hemoproteins such as the cytochromes needed for oxidative phosphorylation. Most studies on heme regulation have been done in...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Philip, Mary, Funkhouser, Scott A., Chiu, Edison Y., Phelps, Susan R., Delrow, Jeffrey J., Cox, James, Fink, Pamela J., Abkowitz, Janis L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323866/
https://ncbi.nlm.nih.gov/pubmed/25582857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402172
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