Pluripotency-associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency

The molecular mechanism controlling the dismantling of naive pluripotency is poorly understood. Here we show that microRNAs (miRNAs) have important roles during naive to primed pluripotency transition. Dgcr8(−/−) embryonic stem cells (ESCs) failed to completely silence the naive pluripotency program...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Res
Main Authors: Gu, Kai-Li, Zhang, Qiang, Yan, Ying, Li, Ting-Ting, Duan, Fei-Fei, Hao, Jing, Wang, Xi-Wen, Shi, Ming, Wu, Da-Ren, Guo, Wen-Ting, Wang, Yangming
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783473/
https://ncbi.nlm.nih.gov/pubmed/26742694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.2
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