Pluripotency-associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency

The molecular mechanism controlling the dismantling of naive pluripotency is poorly understood. Here we show that microRNAs (miRNAs) have important roles during naive to primed pluripotency transition. Dgcr8(−/−) embryonic stem cells (ESCs) failed to completely silence the naive pluripotency program...

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Publicat a:Cell Res
Autors principals: Gu, Kai-Li, Zhang, Qiang, Yan, Ying, Li, Ting-Ting, Duan, Fei-Fei, Hao, Jing, Wang, Xi-Wen, Shi, Ming, Wu, Da-Ren, Guo, Wen-Ting, Wang, Yangming
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783473/
https://ncbi.nlm.nih.gov/pubmed/26742694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.2
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