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miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency

Enhanced glycolysis is a main feature of pluripotent stem cells (PSCs) and is proposed to be important for the maintenance and induction of pluripotency. The molecular mechanism underlying enhanced glycolysis in PSCs is not clear. Using Dgcr8(−/−) mouse embryonic stem cells (ESCs) that lack mature m...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Cao, Yang, Guo, Wen-Ting, Tian, Shengya, He, Xiaoping, Wang, Xi-Wen, Liu, Xiaomeng, Gu, Kai-Li, Ma, Xiaoyu, Huang, De, Hu, Lan, Cai, Yongping, Zhang, Huafeng, Wang, Yangming, Gao, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365031/
https://ncbi.nlm.nih.gov/pubmed/25603933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490441
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