miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency

Enhanced glycolysis is a main feature of pluripotent stem cells (PSCs) and is proposed to be important for the maintenance and induction of pluripotency. The molecular mechanism underlying enhanced glycolysis in PSCs is not clear. Using Dgcr8(−/−) mouse embryonic stem cells (ESCs) that lack mature m...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Cao, Yang, Guo, Wen-Ting, Tian, Shengya, He, Xiaoping, Wang, Xi-Wen, Liu, Xiaomeng, Gu, Kai-Li, Ma, Xiaoyu, Huang, De, Hu, Lan, Cai, Yongping, Zhang, Huafeng, Wang, Yangming, Gao, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365031/
https://ncbi.nlm.nih.gov/pubmed/25603933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490441
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky