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miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency
Enhanced glycolysis is a main feature of pluripotent stem cells (PSCs) and is proposed to be important for the maintenance and induction of pluripotency. The molecular mechanism underlying enhanced glycolysis in PSCs is not clear. Using Dgcr8(−/−) mouse embryonic stem cells (ESCs) that lack mature m...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365031/ https://ncbi.nlm.nih.gov/pubmed/25603933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490441 |
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