Single-cell triple omics sequencing reveals genetic, epigenetic, and transcriptomic heterogeneity in hepatocellular carcinomas

Single-cell genome, DNA methylome, and transcriptome sequencing methods have been separately developed. However, to accurately analyze the mechanism by which transcriptome, genome and DNA methylome regulate each other, these omic methods need to be performed in the same single cell. Here we demonstr...

Full description

Saved in:
Bibliographic Details
Published in:Cell Res
Main Authors: Hou, Yu, Guo, Huahu, Cao, Chen, Li, Xianlong, Hu, Boqiang, Zhu, Ping, Wu, Xinglong, Wen, Lu, Tang, Fuchou, Huang, Yanyi, Peng, Jirun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783472/
https://ncbi.nlm.nih.gov/pubmed/26902283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.23
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items