Single-cell triple omics sequencing reveals genetic, epigenetic, and transcriptomic heterogeneity in hepatocellular carcinomas

Single-cell genome, DNA methylome, and transcriptome sequencing methods have been separately developed. However, to accurately analyze the mechanism by which transcriptome, genome and DNA methylome regulate each other, these omic methods need to be performed in the same single cell. Here we demonstr...

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Foilsithe in:Cell Res
Main Authors: Hou, Yu, Guo, Huahu, Cao, Chen, Li, Xianlong, Hu, Boqiang, Zhu, Ping, Wu, Xinglong, Wen, Lu, Tang, Fuchou, Huang, Yanyi, Peng, Jirun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783472/
https://ncbi.nlm.nih.gov/pubmed/26902283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.23
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