The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells

Multiple sclerosis (MS) is an inflammatory, demyelinating disorder of the central nervous system that develops in genetically susceptible individuals. The majority of the MS-associated gene variants are located in genetic regions with importance for T-cell differentiation. Vitamin D is a potent immu...

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Foilsithe in:Genes Immun
Main Authors: Berge, T, Leikfoss, I S, Brorson, I S, Bos, S D, Page, C M, Gustavsen, M W, Bjølgerud, A, Holmøy, T, Celius, E G, Damoiseaux, J, Smolders, J, Harbo, H F, Spurkland, A
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783434/
https://ncbi.nlm.nih.gov/pubmed/26765264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.61
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