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The Limits of Linked Suppression for Regulatory T Cells

BACKGROUND: We have previously found that CD4(+)CD25(+) regulatory T cells (Tregs) can adoptively transfer tolerance after its induction with costimulatory blockade in a mouse model of murine cardiac allograft transplantation. In these experiments, we tested an hypothesis with three components: (1)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ito, Toshiro, Yamada, Akira, Batal, Ibrahim, Yeung, Melissa Y., McGrath, Martina M., Sayegh, Mohamed H., Chandraker, Anil, Ueno, Takuya
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783400/
https://ncbi.nlm.nih.gov/pubmed/27014262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00082
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