INTACT B7-H3 SIGNALING PROMOTES ALLOGRAFT PROLONGATION THROUGH PREFERENTIAL SUPPRESSION OF TH1 EFFECTOR RESPONSES

Ligands of the B7 family provide both positive and negative costimulatory signals to the CD28 family of receptors on T lymphocytes, the balance of which determines the immune response. B7-H3 is a member of the B7 family whose function in T-cell activation has been the subject of some controversy: in...

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Detalhes bibliográficos
Main Authors: Ueno, Takuya, Yeung, Melissa Y., McGrath, Martina, Yang, Sunmi, Zaman, Nadia, Snawder, Benjamin, Magee, Ciara N., Gorbatov, Rostic, Hashiguchi, Masaaki, Azuma, Miyuki, Freeman, Gordon J., Sayegh, Mohamed H., Najafian, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822046/
https://ncbi.nlm.nih.gov/pubmed/22733595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242501
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