Isolation of peptides that inhibit binding of basic fibroblast growth factor to its receptor from a random phage-epitope library.

Basic fibroblast growth factor (bFGF) is known to bind to its cell-surface receptors with high affinity and in a heparin-dependent manner. In an attempt to predict the receptor recognition site on bFGF we screened phage-epitope libraries with monoclonal antibodies DG2 and DE6, which inhibit bFGF bin...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Yayon, A, Aviezer, D, Safran, M, Gross, J L, Heldman, Y, Cabilly, S, Givol, D, Katchalski-Katzir, E
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504274/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10643
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