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Risks of phase I research with healthy participants: A systematic review

BACKGROUND/AIMS: Tragedies suggest that phase I trials in healthy participants may be highly risky. This possibility raises concern that phase I trials may exploit healthy participants to develop new therapies, making the translation of scientific discoveries ethically worrisome. Yet, few systematic...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Trials
Hauptverfasser: Johnson, Rebecca A, Rid, Annette, Emanuel, Ezekiel, Wendler, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783291/
https://ncbi.nlm.nih.gov/pubmed/26350571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774515602868
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