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Risks of phase I research with healthy participants: A systematic review

BACKGROUND/AIMS: Tragedies suggest that phase I trials in healthy participants may be highly risky. This possibility raises concern that phase I trials may exploit healthy participants to develop new therapies, making the translation of scientific discoveries ethically worrisome. Yet, few systematic...

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Detalhes bibliográficos
Publicado no:Clin Trials
Main Authors: Johnson, Rebecca A, Rid, Annette, Emanuel, Ezekiel, Wendler, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783291/
https://ncbi.nlm.nih.gov/pubmed/26350571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774515602868
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