EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib

Expression of TFAP2C in luminal breast cancer is associated with reduced survival and hormone resistance, partially explained through regulation of RET. TFAP2C also regulates EGFR in HER2 breast cancer. We sought to elucidate the regulation and functional role of EGFR in luminal breast cancer. We us...

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Udgivet i:Mol Cancer Ther
Main Authors: De Andrade, James P., Park, Jung M., Gu, Vivian W., Woodfield, George W., Kulak, Mikhail V., Lorenzen, Allison W., Wu, Vincent T., Van Dorin, Sarah E., Spanheimer, Philip M., Weigel, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783288/
https://ncbi.nlm.nih.gov/pubmed/26832794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0548-T
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