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Acyclic cucurbit[n]uril-type molecular container enables systemic delivery of effective doses of albendazole for treatment of SK-OV-3 xenograft tumors

Approximately, 40–70% of active pharmaceutical ingredients (API) are severely limited by their extremely poor aqueous solubility and consequently there is a high demand for excipients that can be used to formulate clinically relevant doses of these drug candidates. Here, proof-of-concept studies dem...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Hettiarachchi, Gaya, Samanta, Soumen K, Falcinelli, Shane, Zhang, Ben, Moncelet, Damien, Isaacs, Lyle, Briken, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783263/
https://ncbi.nlm.nih.gov/pubmed/26756920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00723
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