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Targeted Cucurbit[7]uril Containers Deliver Oxaliplatin to Cancer Cells

Stay on Target: The cucurbit[7]uril derivative 1 which bears a covalently attached biotin targeting ligand allows for the efficient delivery of oxaliplatin as its 1•oxaliplatin complex to cancer cells resulting in enhanced cytotoxicity relative to oxaliplatin alone.

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Bibliografische gegevens
Hoofdauteurs: Cao, Liping, Hettiarachchi, Gaya, Briken, Volker, Isaacs, Lyle
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954956/
https://ncbi.nlm.nih.gov/pubmed/24039074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201305061
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